Immunology and Vaccine Research
Clinical studies include seasonal influenza vaccination, pneumococcal conjugate vaccination, and immune response assessment in adults at elevated infection risk, with attention to mucosal immunity and resident memory lymphocytes.
- Influenza immunogenicity
- Pneumococcal infection prevention
- Respiratory immune memory
Research activity also includes immunological profiling in healthy volunteers and patients with heightened susceptibility to invasive bacterial infection.
Autoimmune and Inflammatory Disease
The sponsor supports research in rheumatoid arthritis, Crohn’s disease, and noninfectious uveitis, with interest in treatment optimization, biomarker-guided care, and disease control in chronic immune-mediated conditions.
- Rheumatoid arthritis
- Crohn’s disease
- Noninfectious uveitis
Additional work addresses anti-MAG neuropathy and immune-related ophthalmological and neurological outcomes.
Nephrology and Renal Immunology
Research focuses on IgA nephropathy and kidney function preservation, including studies in patients with persistent albuminuria and declining glomerular filtration rate.
- IgA nephropathy
- Renal function decline
- Biopsy-proven kidney disease
This area reflects interest in immune-mediated kidney injury and long-term renal outcomes.
Haematology, Oncology, and Supportive Care
Ongoing studies cover hematological malignancy, relapsed/refractory multiple myeloma, and thrombocytopenia associated with intensive treatment, with attention to bleeding control and antithrombotic management.
- Multiple myeloma
- Hematological malignancy
- Thromboembolism prophylaxis
Research also includes acute venous thromboembolism, anticoagulation, and transfusion-related support in patients with cancer.
Critical Care, Surgery, and Metabolic Neurology
The sponsor is active in sepsis, critical care antimicrobial optimization, and perioperative blood management, alongside studies in hip arthropathy and total hip replacement.
- Sepsis
- Critical care dosing
- Perioperative haemostasis
Additional research addresses anorexia nervosa and neuroimaging of serotonergic transmission in brain circuits involved in food intake.
